In the present study, we investigated the effect of dietary niacin
addition on hepatic fatty acid metabolism in rabbits, and determined the possibility of niacin
attenuates hepatic lipid accumulation.
Although several of the ingredients are known to cause toxicity with overdose, none of their toxicity profiles include hepatotoxicity, except vitamin B3 - niacin
has a modest effect on lowering "bad" LDL-cholesterol levels, but has been prescribed to raise "good" HDL cholesterol.
has been used to decrease serum cholesterol levels in patients at risk of developing cardiovascular disease.
The risk of nonfatal myocardial infarction was lower in patients who had not taken statin drugs but who took niacin
tablets utilize a unique polygel controlled-release system--not available in other dietary supplement niacin
products--that gradually releases nicotinic acid into the body and is designed to reduce the likelihood of flushing, which is commonly associated with immediate-release niacin
We believe that [our] findings are likely to be generalizable to all high-dose niacin
formulations," and any potential benefits of the therapy must be weighed against those important hazards, reported Martin J.
The side effect of Niacin
has always been flushing.
is a type of B vitamin long sold over the counter and in higher prescription doses.
According to the company, research demonstrates supplemental niacin
reduces metabolic problems in dairy herds like ketosis and can result in increased milk production and healthier cows.
Washington, Oct 1 ( ANI ): The vitamin niacin
has a life-prolonging effect, and scientists from ETH Zurich have demonstrated this in roundworms.
The addition of niacin
was implemented in response to a high prevalence of the deficiency disease pellagra (1,2).
has been used for many years to raise HDL "good" cholesterol and reduce LDL "bad" cholesterol by helping to prevent the breakdown of fat.
SAN FRANCISCO -- The largest-ever randomized trial of niacin
for cardiovascular protection has not only failed to show clinical benefit, it spotlighted a hitherto underrecognized and disturbingly high range of serious harms in users of the HDL-raising drug.
in large doses, blocks the breakdown of fats in adipose tissue, thus altering blood lipid levels, so it is used in the treatment of hyper-lipidemia.