Developmental origins of renal disease: should nephron
protection begin at birth?
Hyperfiltration in these nephrons
results form elevations in the mean glomerular transcapillary hydraulic pressure gradient (AP) and plasma flow rate (Qa).
Pre-renal causes generally arise due to hypoperfusion of the nephrons
due to shock, heart failure, hypotension, dehydration, hypovolvaemia or renal arterial stenosis, which all decrease renal blood flow and may trigger renal failure.
In the genital kidney, the testes communicate with the Wolffian ducts through a set of ducts that are modified nephrons
with variable morphologies (for review see Williams et al.
E-cadherin-null mice show decreased nephrons
due to a failure of proper fusion of metanephric mesenchyme to the ureteric bud (Mah et al.
The answer lies in examples such as the relationships between villus structure and nutrient absorption in the small intestine (Figure 1), nephron
structure and water retention in the kidneys (Figure 2), alveolus structure and gas exchange in the lungs (Figure 3), root-hair structure and nutrient absorption in plants, leaf ventation and nutrient transport (Figure 4), and any other function in which surface area is key to life support.
The aglomerular nephrons
of terminal Bright's disease.
Diuretics like Lasix (furosemide) that inhibit the absorption of sodium chloride in the nephrons
result in loss of sodium chloride in the urine.
When tests show that their nephron
numbers are marginal, Brenner advocates transplanting kidneys from brain-dead donors in pairs, and hence delivering more nephrons
Additional features like the Nephron
oil filtration system and the One-Touch Decelerator make these machines conservative with fuel while extending their operating life.
A ball of small blood capillaries (a glomerulus) and a small tube called a renal tubule comprise a nephron
The LX Series also features the Nephron
Filtration System, designed to eliminate contaminants down to the size of one micron from the hydraulic system.
consists of a ball formed of small blood capillaries, called a glomerulus, and a small tube called a renal tubule.
The physician's note, of course, just reflected that I had stopped the procedure, not that I had received inadequate instructions or anesthesia, or that my kidneys may have lost a nephron
or two from a rapid gentamicin infusion.
Tumour cells have some features of proximal nephron
differentiation, and others related to distal nephron