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Related to monomorphic adenoma: Pleomorphic adenoma, Canalicular adenoma
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of False Neoplastic Site ([dagger]) dagger]) Diagnoses by Pathologists Liver 180 37 Hepatocellular adenoma, 36 Hepatocellular carcinoma, 21 Benign neoplasm NOS, 5 Metastatic carcinoma NOS, 1 Metastatic small cell carcinoma, 1 Adenocarcinoma (primary or metastatic), 2 Pancreas 171 10 Islet cell or neuroendocrine tumor, 12 Microcystic adenoma, 1 Lympoma, 1 Adenocarcinoma, 1 Carcinoma NOS, 1 Benign neoplasm NOS, 1 Salivary 272 6 Acinic cell carcinoma, 4 gland Squamous cell carcinoma, 2 Monomorphic adenoma, 3 Adenoid cystic carcinoma, 1 Warthin tumor, 1 Benign neoplasm NOS, 5 Kidney 102 60 Renal cell carcinoma, 59 Angiomyolipoma, 1 Metastatic carcinoma NOS, 1 * FNA indicates fine-needle aspiration; NOS, not otherwise specified.
Because PLGAs share many of the histologic characteristics of pleomorphic adenomas, monomorphic adenomas, adenoid cystic carcinomas, and low-grade papillary adenocarcinomas, these other tumors should be considered in the differential diagnosis of PLGA.
We describe the case of a patient with a parotid mass that was found to consist of both a facial nerve schwannoma and a monomorphic adenoma.
It is our opinion, as well as that of Barnes et al [5] and Dardick et al [15] that salivary adenomas are part of a spectrum, with monomorphic adenoma and myoepithelioma at the extremes and a wide range of pleomorphic adenomas in between, depending on the type and degree of gene expression that is coupled with neoplastic transformation.
2) It is situated at one end of a biologic spectrum that includes pleomorphic adenomas and other monomorphic adenomas.