monogenic


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Related to monogenic: monogenic disease
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Words related to monogenic

of or relating to an inheritable character that is controlled by a single pair of genes

References in periodicals archive ?
It must be pointed out that the same argument does not apply to monogenic diabetes.
Monogenic diabetes is often misdiagnosed as either type 1 or 2 diabetes, and as such patients are often treated inappropriately.
The company also intends to expand the study of gene therapy into two additional rare neurological monogenic disorders: Rett syndrome and a genetic form of amyotrophic lateral sclerosis caused by mutations in the superoxide dismutase 1 gene.
Monogenic hypercholesterolemia: new insights in pathogenesis and treatment.
5) that describe the genotype and phenotype probabilities for monogenic Mendelian inheritance.
1) The genetic basis of monogenic autoinflammatory diseases (MAD) and the importance of genetic diagnosis
A goodness of fit test was used to test for monogenic inheritance, double recessive epistasis, and oligogenic or polygenic character in the [F.
A chi-square test ([chi square]) was used to verify the hypothesis of dominant monogenic inheritance (3R:1S).
One should emphasize the association of FMF as a monogenic autoinfammatory disease, and coexistent H.
The researchers have a particular interest in finding new treatments for genetic forms of diseases like monogenic diabetes and Hirschsprung's disease.
This rare monogenic autoimmune disorder commonly encompasses autoimmune hematological disorders (identified in 70% of patients), recurrent infections (60%), and autoimmune enteropathies (50%) (1-3).
Haemoglobinopathies are not the most common monogenic disorders in SA, but from the data summarised above it is clear that they do occur at significant frequencies in high-risk minority groups, and when detected appropriate genetic counselling can be offered.
Other topics include the evolution of gene regulation in humans, the properties of long non-coding RNAs that regulate chromatin, the developmental origins of common disease: epigenetic contributions to obesity, old dogs and new tricks: monogenic autoinflammatory disease unleashed, defining the clinical value of a genomic diagnosis in the era of next-generation sequencing, and broad consent for genome research and biobanking: perspectives from low-income and middle-income countries.
Mill, and Harriett Martineau all acted as influences for Darwin's monogenic account of how natural and sexual selection could by themselves account for the moral and social evolution of humans.
Relatively speaking, that's a common monogenic (single-gene) cause of obesity," he said.