Lesson of the week: microbial keratitis
in intensive care.
7%) and the association between corneal injury and culture-proven microbial keratitis
was significant (P<0.
Currently, microbial keratitis
is treated with antibiotics, but the recent emergence of resistant bacterial strains has heightened the need for alternative treatments, making the development of new therapies an important field of research.
Contact lenses remain the greatest single risk factor for sight-threatening microbial keratitis
, however rare, and we, as a profession, and industry are overwhelmingly involved in their fitting and distribution.
McDonnell's research interests include the causes and correction of refractive error, corneal wound healing and microbial keratitis
These are vey promising early results that point to potentially new methods for removing bacterial biofilms from contact lens surfaces, thereby reducing the risk of microbial keratitis
, as well as the for the treatment of infections by Pseudomonas that are associated with cystic fibrosis and severe burns," said Danielle Robertson, first author and Assistant Professor of Ophthalmology at UT Southwestern, and first author on the study.
It heavily increases the risk of microbial keratitis
, a devastating condition which can lead to permanent blindness through infection of the cornea.
The American Academy of Ophthalmology (Academy), the Contact Lens Association of Ophthalmologists (CLAO), the Cornea Society and the American Society of Cataract and Refractive Surgery (ASCRS) urged the changes as experts report that the number of cases of microbial keratitis
, particularly Acanthamoeba keratitis, among contact lens wearers remain steady, despite attempts to improve contact lens disinfection regimens over the years and voluntary recalls of contact lens solutions associated with keratitis outbreaks in 2006 and 2007.
Further to this, the app includes a number of short factsheets about eye conditions which are related to contact lenses, from bacterial conjunctivitis to microbial keratitis
as a foreseeable complication of cosmetic contact lenses: A prospective study.
A suspect microbial keratitis
is a well-recognised ocular emergency and requires prompt referral and treatment into ophthalmology.
Collagen Cross-Linking with Photoactivated Riboflavin (PACK-CXL) for the Treatment of Advanced Infectious Keratitis with Corneal Melting Corneal collagen cross-linking with ultraviolet A light and photoactivated riboflavin may represent a promising adjuvant therapy in the treatment of advanced microbial keratitis
associated with corneal melting.
1) Furthermore, cases of vision-threatening microbial keratitis
associated with orthokeratology practice in both adults and children are well documented in the literature.
In a study of over 400 cases of microbial keratitis
in San Francisco between 1976 and 1999, only 8% were due to fungi.
By not following instructions on proper wear and care, contact lens wearers are more likely to experience discomfort and may put themselves at greater risk for infection or other serious complications, such as microbial keratitis
," she notes.