Easier access to the marrow space
from an anterior or posterior position with reduced risk of unintended surgical trauma because the flexible needle will not penetrate cortical bone.
The transplanted bone marrow cells migrate to the marrow space
and actually begin the process of repopulation.
Design features ensure easy identification of the site, quick and accurate penetration to the correct depth in the bone marrow space
, resistance to strain and external forces, and immunity to interference with other procedures.
As shown in Figure 4, PMMA filled the marrow space
in the expected trabecular pattern.
On microscopy, the bone marrow trephine biopsy specimen had a cellularity of 98% (fat cell ratio, 2:98), and the marrow space
was almost completely effaced by an infiltrate of myeloid and monocytic cells, which immunohistochemically were positive for myeloperoxidase.