The macula appears as a yellow spot in the retina, due to the presence of zeaxanthin, lutein, and meso-zeaxanthin.
Although other carotenoids can be found in the foods we eat, only zeaxanthin and lutein accumulate in the macula.
In macular degeneration, abnormal deposits called drusen develop in the retina and macula, damaging this cellular layer.
Just as these carotenoids protect the eye's macula and lens, they may similarly protect the skin against detrimental age-related changes, such as reduced flexibility, hydration, and lipid content.
Patients with macular degeneration have been shown to have 30% less meso-zeaxanthin in their macula compared to healthy eyes.