was, however, more common among HIV-infected patients, most likely due to the use of azidothymidine.
15) Folate intakes were low but RBC folate levels, at least among young women, were not in a range associated with macrocytic anaemia
There was a statistically significant difference between males and females in patients with macrocytic anaemia
and low B12 values (pless than 0.
Other more common complication\' are Macrocytic anaemia
and sub acute combined degeneration of spinal cord.
Macrocytosis with anaemia or macrocytic anaemia
may be with a megaloblastic change in the bone marrow or with a non-megaloblastic change in the bone marrow.
Zidovudine (AZT), especially when used as a single agent, is the drug historically most frequently implicated in HIV-related anaemia; a dose-dependent macrocytic anaemia
In a case series of 225 patients undergoing primary THR, 35 were anaemic: 60% were iron deficient, 34% had a normochromic normocytic anaemia and 6% had a macrocytic anaemia
It also helps prevent macrocytic anaemia
, a disease in which blood cells grow larger than normal, and have a shorter lifespan.
This leads to the release of immature RBCs called macrocytes, which function less efficiently and produce macrocytic anaemia
The hallmark of folate deficiency is macrocytic anaemia
with megaloblastic change in the bone marrow.
On admission, the patient had a macrocytic anaemia
(MCV 108 fL and Hb 106 g/L), with target cells and toxic changes seen in the blood film.
In the paediatric group, 30% of patients with coeliac disease were found to have IDA (19), whereas in the adult group of coeliac disease, macrocytic anaemia
due to folic acid deficiency was found in 30% of patients (18).
Anaemia was noticed in fourteen cases- normocytic normochromic anaemia was seen in six cases, macrocytic anaemia
was seen in five cases, dimorphic anaemia was seen in three cases.
Only a small number of our patients had macrocytic anaemia
Comparison of Peripheral Blood Smear in Alcoholic and Non-alcoholic Patients Peripheral Blood Alcoholics Non Smear (n=185) (n=315) Normocytic Normochromic 13(7%) 23(7%) Anaemia Normal 48(26%) 197(63%) Macrocytic Anaemia
48(26%) 32(10%) Microcytic hypochromic Anaemia 28(15%) 37(12%) Dimorphic Anaemia 32(17%) 11(4%) Thrombocytopenia 9(5%) 10(4%)