In the pharmaceutical and health fields, models exist to calculate the potency of substances to cause skin sensitisation, irritancy, corrosivity, lachrymation
, methaemoglinaemia, mutagenicity, carcinogenicity, teratogenicity, and many other effects.
Nat mur Weakness, photophobia, itchy eyes, lachrymation
, swelling of the eyes and migraine headaches that are worse from sunrise to sunset, numbness and tingling of the tongue, sneezing and coryza may be seen here.
Because they are powerful inhibitors of carboxylic ester hydrolases, including acetyl-cholinesterase (AChE; found in nerve tissues and erythrocytes) and butyrylcholinesterase (plasma or pseudocholinesterase), individuals exposed to high levels of OPs can develop acute cholinergic syndrome, which is characterized by a variety of symptoms including rhinorrhea, salivation, lachrymation
, tachycardia, headache, convulsions, and death (Karalliedde et al.