The exocrine pancreas is found throughout the organ; within the exocrine pancreas, distinct cell masses called islets of Langerhans are dispersed and constitute the endocrine pancreas.
T1D is characterized by lymphocyte infiltration into the islets of Langerhans in the pancreas, leading to inflammation and selective destruction of the insulin-producing 3-cells, resulting in hyperglycemia (1).
History has shown us that student research can have big impact for the entire scientific community; the discovery of Islets of Langerhans as well as Insulin are some of the groundbreaking discoveries contributed by medical students (1).
Unniappan's findings indicate that the protein stimulates insulin secretion from the pancreas, a glandular organ, which contains clusters of cells called the islets of Langerhans.
During alloxan treatment, [beta]-cytotoxin causes a massive destruction of [beta]-cells in islets of Langerhans, and reduces the [beta]-cells and insulin release (Colca et al.
Endocrine function--A minute but crucially important portion of total pancreatic mass is made up of tissue containing small clusters of cells called islets of Langerhans.