Future prospective echocardiographic studies examining the relationship between aorto-ostial involvement, aortic intimal
thickness, and coronary involvement will be instrumental in providing information that can be used to detect patients at a high risk for coronary dissection.
Results: TPNS significantly inhibited the vascular intimal
Dissection is diagnosed on contrast-enhanced CT angiography (CTA), which allows visualization of both true and false channels, the intimomedial flap, and often, the intimal
The LDL receptor relative with 11 ligand-binding repeats (LR11)  (also known as SorLA) (1, 2) is a member of the LDL receptor family and is highly expressed in atheromatous plaques, particularly in the intimal
smooth muscle cells (SMCs) at the border between the arterial intima and the media (3).
These include transplant arteriopathy, restenosis lesions after balloon angioplasty and stenting, intimal
nonatherosclerotic proliferative lesions in arterial vessels larger than arterioles, and a variety of disorders associated with vascular calcification, not generally regarded as Monckeberg sclerosis.
They also underwent computed tomography of the chest to assess coronary artery calcium (CAC); B-mode ultrasound to evaluate the intimal
medial thickness of the internal carotid artery (ICA IMT) and of the common carotid artery (CCA IMT); and magnetic resonance imaging to determine the left ventricular (LV) mass, the authors reported.
The smooth muscle in the medial layer of the pulmonary arteries undergoes hypertrophy, and the intimal
lining of the arteries and arterioles experiences fibrosis.
A retired cardiologist from Papworth Hospital in Cambridge proposes that the inception of coronary arterial disease is associated with an undue multiplication of intimal
arterial cells, that it is not lipid- related, and that its development is encouraged by factors in the environment which control such multiplication.
Surgically, aortic dissection type A with an intimal
tear above the aortic valve was found and an aortic Vascutek 32 mm prosthesis was implanted.
Aortic rings without endothelium were prepared by gently rubbing the intimal
surface of the aortic rings with a wooden stick.
Similarly, the increase in maximal intimal
thickness was lower in the everolimus groups vs the azathioprine cohort.
The primary endpoint was the change in average intimal
index (plaque area divided by vessel area) measured by intravascular ultrasonography (IVUS).
Sirolimus is a new drug that prevents the proliferation of smooth muscle cells, the principal culprit in intimal
The earliest lesions of atherogenesis consist of arterial intimal
accumulations of foam cells (primarily lipid-laden macrophages) and T lymphocytes intermixed with smooth muscle cells (7).
The device is designed to address the most common causes of graft failure; intimal
hyperplasia, thrombosis, and seroma.