Once released into circulation, interleukin-1-beta
signals the activation of more and more immune cells and inflammatory proteins, resulting in a destructive inflammatory response.
Her in vitro studies showed that cherry juice concentrate reduced by up to half interleukin-1-beta
and tumor necrosis factor-alpha secretion by monocytes exposed to monosodium urate crystals.
Subjects with obesity tend to have more abdominal visceral adipocytes, which are supposed to produce almost 25% of systemic interleukin-6 in vivo; (19) and CRP could be stimulated by cytokines such as interleukin-1-beta
, interleukin-6 and tumor necrosis factor-[alpha].
In test-tube experiments, sorghum bran significantly reduced white blood cells' production of several inflammation-linked chemicals, including the immune-system activators tumor-necrosis-factor-alpha (TNF-alpha) and interleukin-1-beta
The team found increased levels of the cytokines interleukin-6 and interleukin-1-beta
in the skeletal and cardiac muscle of mice that received lipopolysaccharide, yet among those that received vitamin E, levels of these cytokines were significantly lower than those of the placebo group.