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  • noun

Words related to interferon

an antiviral protein produced by cells that have been invaded by a virus

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Successful treatment with novel triple drug combination consisting ofinterferon-gamma, interferon alfacon-1, and ribavirin in a nonresponder HCV patient to pegylated interferon therapy.
Table 2 Drugs for the Treatment of Chronic Hepatitis C Immunomodulators Interferon alfa-2a (Roferon[R], Roche Pharmaceuticals) interferon alfa-2b (Intron A[R], Schering Corporation) Interferon alfacon-1 (Infergen[R], Valeant Pharmaceuticals) Peginterferon alfa-2a (Pegasys[R], Roche Pharmaceuticals) Peginterferon alfa-2b (PegIntron[R], Schering Corporation) Antiviral Ribavirin (Copegus, Rebetol, Ribasphere, and other manufacturers) Drugs Currently in Advanced Stages of Development * Albinterferon alfa-2b (Albuferon[R], Human Genome Sciences, Inc.
There are several FDA-approved therapies for chronic hepatitis C: interferon alfa-2b, interferon alfa-2a, interferon alfacon-1, peginterferon alfa-2b, peginterferon alfa-2a, and each, except for interferon alfacon-1, in combination with ribavirin.
Leading the hepatology portfolio is the DIRECT trial, an ongoing Phase III study of daily interferon alfacon-1 (Infergen) plus ribavirin, and an ongoing Phase II trial of daily interferon alfacon-1 plus interferon gamma-1b (Actimmune) with and without ribavirin.
The interferon alfa agents include interferon alfa-2a (Roferon-A), peginterferon alfa-2a (Pegasys), interferon alfa-2b (Intron A), peginterferon alfa-2b (Peg-Intron), interferon alfacon-1 (Infergen), and interferon alfa-n3 (Alferon N).