The presentation of acute lymphoblastic leukemia (ALL) may be atypical with hypercalcemia
, bone lesions, and absence of circulating blasts, making the diagnosis very difficult.
Overproduction of PTH-related peptide by tumors is a common cause of hypercalcemia
that is associated with malignancy.
may occur during paricalcitol treatment and may be exacerbated by concomitant administration of high doses of calcium containing preparations, thiazide diuretics, or vitamin D compounds.
In the 1950s, there were about 200 reported cases of infantile hypercalcemia
in Britain during a period of high vitamin D supplementation (up to 4000 IU per day) in fortified milk products.
Laboratory examination revealed elevated serum calcium, and the patient was referred to endocrinology outpatient clinic for further investigation of hypercalcemia
with a preliminary diagnosis of brown tumors secondary to hyperparathyroidism.
persists after surgery, periodic bisphosphonate therapy may help lower serum calcium levels.
did not recur after the first cycle of ABVD.
Her medical history was remarkable for 2 hospitalizations for hypercalcemia
that resolved with rehydration.
in the presence of inappropriately elevated parathyroid hormone concentration is suggestive of PHP.
However, in patients with hyperparathyroidism and resulting hypercalcemia
, pancreatitis occurs 10 to 20 times more often than in the general population.
A 45-year-old man with a history of hypercalcemia
and cervical exploration at the age of 33 years presented with recurrent hypercalcemia
(calcium level 3.
Of Malignancy - Pipeline Review, Q3 2011', provides an overview of the Hypercalcemia
Of Malignancy therapeutic pipeline.
occurs, patients are advised to stop using Sorilux Foam until calcium levels return to normal.
There was no recurrence of hypercalcemia
after discharge from the hospital.
The main basis for the argument that 10,000 IU per day is safe is that it has not been found to cause hypercalcemia
in clinical trials.