Coverage of the Hairy Cell
Leukemia pipeline on the basis of route of administration and molecule type.
35-37) Hairy cell
leukemia cells express CD25, CD103, and bright CD11c and CD22, a pattern not observed in other B-cell non-Hodgkin lymphomas.
Kaposi's sarcoma, hairy cell
leukoplakia were other associated health problems.
Heterogeneity of hairy cell
tartrate-resistant acid phosphatase.
Estimates on the incidence of hairy cell
leukemia vary, but there are an estimated 1,000 patients, primarily middle-aged men, in the United States.
2) (a) Other includes textual answers including all lymphomas, B cell lymphoma, T cell lymphoma, non-Hodgkin lymphoma, hairy cell
leukemia, Sezary syndrome, myelodyplastic syndrome, and acute leukemias.
8 September 2011 - US developer of transrenal molecular diagnostics TrovaGene Inc (PINK:TROV) said yesterday it has entered into an exclusive licence agreement for an assay that detects Hairy Cell
The illnesses affected by the recent decision are B cell leukemias, such as hairy cell
leukemia; Parkinson's disease; and ischemic heart disease.
In hairy cell
leukemia, however, serum band 5 TrACP activity remains within the reference interval for otherwise healthy persons, in spite of extremely high enzyme activity in the leukemic cells .
Leukemia Global Clinical Trials Review, H1, 2012" provides data on the Hairy Cell
Leukemia clinical trial scenario.
Vemurafenib, an inhibitor of BRAF, has already been shown to be effective in the treatment of melanoma and hairy cell
leukemia that harbor BRAF mutations.
Pestka was the first to develop a genetically engineered biotherapeutic, the interferon-based drug Roferon A, in 1986 for treatment of hairy cell
We will restrict our discussion to the following B-cell neoplasms that characteristically exhibit prominent splenomegaly without significant lymphadenopathy: splenic marginal zone lymphoma (SMZL), hairy cell
leukemia (HCL), and unclassifiable SLs (including the provisional World Health Organization entities HCL variant [HCL-v] and splenic diffuse red pulp small B-cell lymphoma [SDRPL]).
Pink Sheets: TROV), a developer of transrenal molecular diagnostics to facilitate personalized medicine, has signed a worldwide exclusive license for an assay that detects Hairy Cell
For example, surface immunoglobulin and CD20 expression are typically dim in CLL/SLL but are brighter in other small B-cell neoplasms and especially bright in MZL and hairy cell