7 people experienced granulocytopenia
and clozapine was discontinued for them.
ADVERSE EFFECTS OF All IN CHILDREN * Class Drug Adverse effects NRTls AZT Anaemia, granulocytopenia
, myopathy, lactic (Retrovir[R]) acidosis ddl Common: abdominal pain, nausea and vomiting (Videx[R]) Uncommon: diarrhoea, pancreatitis, peripheral neuropathy, lactic acidosis Stavudine Common: headache, rash, gastro-intestinal, (Zerit [R]) lipo-atrophy Uncommon: pancreatitis, peripheral neuropathy (adults), lactic acidosis Abacavir Hypersensitivity reaction (with or without (Ziagen[R]) rash)--fever, rash, fatigue, nausea, vomiting, diarrhoea, pharyngitis, dyspnoea, cough Elevated ALT, creatinine or CK.
Underlying factors specific to PAB included for analysis were invasive procedures, systemic corticosteroid therapy, cytotoxic therapy, surgery, intravascular catheters, granulocytopenia
and ICU admission.
versus cyclosporine and methylprednisolone-induced immunosuppression.
Agranulocytosis and granulocytopenia
are seldom reported with other antipsychotics, so a blood cell count is only warranted when clinical features of leucopenia are present (e.
complicating colchicine therapy for primary biliary cirrhosis.
Significance of serum bactericidal activity in gram-negative bacillary bacteremia in patients with and without granulocytopenia
13) Later, Garcia et al published a case report and literature review in which they noted that 50% of patients with Kikuchi' s disease had mild granulocytopenia
Clozapine can cause serious side effects, such as granulocytopenia
, sedation, and orthostatic hypotension.
and defects of B cells or complement compartment must be excluded (17).
The whole panoply of blood diseases is seen: thrombocytopenia with its loss of white blood cells that guard against infection; severe bone marrow hypoplasia; inability to synthesize fibrinogen; abnormally long bleeding time; granulocytopenia
Growth factors have a wide range of opportunities, especially in treating critical conditions such as granulocytopenia
, leukemia, aplastic anaemia, bone marrow transplantation, and myelodysplastic syndrome.
In conclusion, we want to emphasize the potential for serious side effects that affect the immune system in polypharmacy diabetic patients, such as granulocytopenia
, and the importance of pharmacovigilance in patients with chronic diseases and the risk of comorbidity.
001), and; granulocytopenia
or a lowering of granulocyte white blood cells (78 vs.
Those considered at high risk had 4 or more of the following risk factors: present or recent past treatment with broad-spectrum antibiotics and/or chemotherapy, granulocytopenia
(neutrophils [is less than] 1.