19) In the Asia-Pacific and European regions, for instance, gonococci
have been observed to need increased concentrations of antibiotics to stop them multiplying.
Results from this study and other studies in China had suggested that Ser91 mutation might play an important role in mediating quinolone resistance in gonococci
The development of antibiotic resistance among gonococci
continues to threaten the success of the syndromic management in many of the world's poorest regions where the prevalence of gonorrhoea is often highest.
In this study, we used both conventional bacteriologic methods and a novel real-time PCR assay to identify all gonococci
isolated in New Caledonia since July 2003 and to determine whether phenotypes obtained by E-test correlate with genotypes identified by melting curve analysis after amplification of specific gene sequences.
The peptide deformylase inhibitors have shown in vitro activity against Chiamydia species, gonococci
, spirochetes, and Haemophilus ducreyi.
We streak bi-plates for gonococci
and perform a two-glass (split urinalysis) on specimens from male patients to help doctors distinguish between involvement in the urethra, suggesting gonococcal involvement, and in the bladder.
Animal studies showed that the microbicide prevented the transmission of gonococci
, herpes virus and chlamydia when it was placed in the vagina before inoculation of the pathogens.
In 2009, the Australian Gonococcal Surveillance Programme reported that 43% of tested gonococci
were resistant to ciprofloxacin; however, [approximately equal to] 33% of those infections were acquired overseas (32).
2, a level that has been proven in early clinical testing to render sperm immobile and inactivate most STI-causing organisms, including gonococci
, herpes, Chlamydia, HPV and HIV.
For example, rapid results of throat cultures for group A streptococci or of genital cultures for gonococci
and Chlamydia trachomatis in outpatients can guide an early therapeutic decision.
Preclinical testing has also shown it to inactivate several STI-causing organisms, including gonococci
, herpes, chlamydia and HIV.
The in vitro studies provide evidence that solithromycin is active against gonococci
, including resistant strains, and positions us well as we begin clinical development for urethritis.
Other studies have listed factors that may facilitate spread of asymptomatic gonococcal infection, such as pregnancy (1,8), menstruation, viral hepatitis, differences in virulence between strains of gonococci
, and host immunologic differences.