In specimens received from prophylactic gonadectomy
procedure, it is important to appreciate the underlying genetic condition to perform an appropriate pathologic examination.
Roles of gender, gonadectomy
and estrous phase in the analgesic effects of intracerebroventricular morphine in rats.
Sex differences in response rates during random-ratio acquisition: effects of gonadectomy
The investigators excluded patients with primary hypogonadism, surgical gonadectomy
, and medical conditions such as anorexia nervosa, hypothyroidism, and hypopituitarism that could lead to hypogonadism.
did not, however, prevent rats from providing the differential olfactory cues to support patterned responding in conspecifics.
1999) The effects of gonadectomy
on bone size, mass and volumetric density in growing rats are gender, site and growth hormone specific.
Gonadal hormones appear to provide a tonic inhibitory function on the thymus; gonadectomy
in adulthood leads to an increase in thymic tissue, whereas estrogen can produce thymic involution.
2 McNeese (1975) reported other useful observations, partially discussed above: (a) Gonadectomy
did not disrupt the response patterning, ruling out a whole set of possible anatomical odor sources; (b) Fluorescent markings arising from urine were greater on N than R trials, but greatly suppressed by gonadectomy
, though gonadectomy
did not reduce basal rate of urination; this elaborated and made precise earlier observations by Pratt (1970); (c) Fluorescent markings were unrelated to response patterning (see Ludvigson & Duell, this issue, for discussion); and (d) Both paper flooring and the air over it seemed to be sources of episodic odors, suggesting a fairly volatile substance, a finding later confirmed by Taylor and Ludvigson (1980b) (see Taylor, this issue, for discussion).