He added, "I believe our team is well-positioned so that we are not just a neuroscience opportunity but a company that can address multiple pathologies associated with the glutamate
In a study on rodents, investigators from the National Institute on Drug Abuse used tracers to confirm that the reward pathways started with glutamate
cells in the dorsal raphe nucleus, which connect to dopamine cells in the ventral tegmental area, which eventually lead to the nucleus accumbens, a brain structure important to reward, pleasure, and motivation.
Two classes of glutamate
receptors exist: ionotropic receptors (iGluRs), and metabotropic receptors (mGluRs).
The amino group went back from glutamate
So, only a significant depolarization-such as that caused by the activation of AMPA type glutamate
receptors-will unblock the [Mg.
It has long been thought that glutamate
may be one of the chemical causes of depression.
The pyruvate gets converted to glutamate
by serum glutamate
Oxidative stress, glutamate
, and neurodegenerative disorders.
The study carried out by scientists from NeuroCure Cluster of Excellence at Charite -- Universitatsmedizin Berlin and Baylor College of Medicine in Houston, Texas, shows that a certain type of protein -- the "vesicular glutamate
transporter" (VGLUT) plays a crucial part in the strength regulation of synaptic connections.
A previous study found that mice without a protein responsible for transporting glutamate
in the brain suffer from epileptic seizures.
Other researchers found that hypocretin has a negative feedback relationship with GABA and a positive feedback relationship with the excitatory neurotransmitter glutamate
THE EUROPEAN Union (EU) Council of Ministers has authorised definitive anti-dumping duties on imports into the EU from China of two key inputs: monosodium glutamate
and citric acid.
The researchers report the effects of tampering with dopamine and another chemical messenger, the glutamate
neurotransmitter, along the length of the nucleus accumbens of rats.
The importance of the protein glutamate
to normal brain function is explored in this textbook, part of Humana's The Receptors series.
It is a common food additive in the form of monosodium glutamate
(MSG), and is linked with "Chinese restaurant syndrome.