neglecta caused tubular damage in some regions, but no damage and/or change was observed in the structure of glomeruli
and Bowman capsule as the most important parts of the kidneys.
Induction of reactive oxygen species from isolated rat glomeruli
by protein kinase C activation and TNF-[alpha] stimulation, and effects of a phosphodiesterase inhibitor.
A: Coarse tubular intracytoplasmic brown granules, glomeruli
are completely spared (hematoxylin and eosin stain 400x); B: Coarse Fontana positive cytoplasmic granules (100x); C: Intratubular granules negative in modified Ziehl Neelsen for lipofuscin (100x).
Classic pathway of complement activation in normal and diseased human glomeruli
One control animal had evidence of proliferative glomerulonephritis, but only approximately 10% of glomeruli
The rate of filtration remains elevated or at near-normal levels, and the glomeruli
begin to show damage.
High blood sugar and high blood pressure damage the kidneys' glomeruli
Transforming growth factor-beta1 (TGF-[beta]1), a multifunctional cytokine, is a key mediator of diabetic nephropathy and increases glomeruli
expression of ECM proteins, such as collagen 1, collagen IV, laminin, and fibronectin (Grande et al.
Meanwhile, we also conducted a kidney biopsy which showed the presence of mesangial and endocapillary proliferation, segmental sclerosis of the glomeruli
, and mild interstitial fibrosis/ tubular atrophy.
show a constellation of findings, including a diffuse form with mesangial sclerosis and uniform thickening of capillary loops, nodular lesions recognized as KW lesions, exudative or segmental hyalinosis lesions, and the subcapsular capsular drops.
Parts of the mouse brain called glomeruli
get signals from mice's smell-sensing nerve cells.
By definition, patients with WHO class III have less than 50% of the volume of an individual glomerulus or less than 50% of the total number of glomeruli
with endocapillary proliferation.
However, a few surviving glomeruli
showed features of collapse and wrinkling, consistent with the diagnosis of FSGS.
Kidney biopsy (light microscopy) showed collapse of the glomeruli
with severe vacuolisation of the podocytes (Fig.
34) In these cases, it has been suggested that FSGS was missed in an early biopsy due to a sampling error, or the fact that no juxtamedullary glomeruli
were identified for evaluation.