By harnessing the lineage tracing methods that are available in the fly, Enriquez was able to adapt them to label the glia
and motor neurons born from the same stem cell in two colors.
Neuroscientists began to notice in the early 1990s that glia
are more than just the support crew for neurons.
ions in the axon perfusate was drastically reduced, thereby inducing depolarization of the axon but not of the glia
Our new results show that ensheathing glia
could help overcome the barrier that forms between bridges of growth-promoting Schwann cells and the host spinal cord.
In addition to providing myelin for neurons, glia
may also supply nutrients for the nerve cells, guide and direct axon outgrowth, maintain chemical balance in the environment surrounding the neurons, and clear out debris after neuronal death or injury.
are critical for normal brain function, development and response to injury.
This is possible because the zebrafish retina contains cells called Muller glia
that harbor a gene that allows them to regenerate.
far out number neurons in the brain and their defects are now known to be associated with many neurological diseases.
Q-Cells are glial-restricted progenitor cells (GRPs) that are early descendants of neural stem cells that produce the glia
that comprise half of the cells in the brain, and are essential for supporting, maintaining and even restoring neuron health.
How oligodendrocytes work together to wrap nerve fibers in myelin becomes evident in Brainbow photos of the roughly 3-millimeterlong optic nerve, the team reports in the April Glia
This book contains papers written and edited by experts in the field that explore the function and development of glia
in great detail.
The study demonstrated that the Fluidigm C1TM Single-Cell Auto Prep System could be used to distinguish and identify similar cell types--such as NPC (neural progenitor cells), primary neurons and radial glia
(which were isolated from different regions of the brain)--from one another.
These Muller glia
cells - a type of adult stem cell - is capable of transforming into the specialised cells in the back of the eye and could be useful for treating a wide range of sight disorders.
The text is divided into three parts: initiation and early direction of the central and peripheral nervous systems, diversification of neuronal function, and development of non-neuronal cells, with a focus on the role of glia
The study, out today in the journal Cell Stem Cell, suggests that the evolution of a subset of glia
called astrocytes -- which are larger and more complex in humans than other species -- may have been one of the key events that led to the higher cognitive functions that distinguish us from other species.