Although coaching has become his new passion Glia
still finds time to play regularly for Oak FC, stars of the popular Expat League.
have certainly gotten short shrift for much of brain science's history, but it remains to be seen whether, as Koob claims, astrocytes are the true "nerve centers" and neurons only highways connecting the hubs of astrocyte activity.
only secrete these thrombospondins early in brain development, concurrent with the normal formation of synapses.
These previous experiments simply showed that the proteins glia
secrete help neurons in a lab dish form synapses.
To get at the question, she looked at patterns of gene expression in Muller glia
from damaged, regenerating zebrafish retinas and from undamaged zebrafish retinas to see which genes are expressed differently in damaged and undamaged retinas.
When applied to nerve cells growing without glia
in a dish, says Barres, "thrombospondin is sufficient to greatly increase the number of synapses.
As a consequence neuroepithelial cells keep multiplying generating a bigger pool of radial glia
, which in turn produce more neurons ultimately resulting in a larger cortex," explains Sahara.
The finding that CPF targets glia
as well as (or perhaps more than) neurons (Barone et al.
make up 90 percent of the cells in the brain, but they have traditionally drawn less interest than have nerve cells, or neurons, which relay electrical signals by releasing chemicals at synapses.
has already been entered in the 2002 Irish 1,000 Guineas.
Down's syndrome, spinal cord injury, Alzheimer's disease, and stroke all are linked by an overproduction of glia
The papers are organized into seven sections that focus on tools for the determination of mitotic propensity in central nervous system cells; postnatal development of neurons and glia
; the regulation of cell cycle in glia
; neurosurgical resections for the treatment of neurological disorders; the possible detrimental effects of cell cycle re-entry; recent advances in the biology and detection of gliomas (a type of tumor arising from glia
cells); and attempts to treat neurological disorders by gene transfer, electrical simulation, or stem cell introduction.
Fourth, to what extent might glia
be affected preferentially to neurons?
Researchers are learning that a host of other nervous system cells, called glia
, have more control than anyone suspected.
But Golderg's work suggests that while glia
cells slow axon growth, they're not the only problem.