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Related to gingival hypertrophy: Dilantin gingival hyperplasia
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A two year old boy with infantile systemic hyalinosis was referred to the Department of Oral Pathology, The Children's Memorial Health Institute, Warsaw, Poland because of gingival hypertrophy that was impairing normal nutrition.
One month after the end of this therapy, the grade of gingival hypertrophy (according to the grading method of Matarasso) had improved from grade 3 to grade 1, and the lip hypertrophy had disappeared.
Gingival hypertrophy, hirsutism and coarsening of facial features are well-recognised adverse effects; however, side-effects such as osteomalacia are often forgotten.
A complete response in a patient with myelodysplasia and; * Significant reduction or elimination of marrow blasts at the end of the first cycle in 5 patients with AML, including resolution of leukemic gingival hypertrophy in one.