The presence of the bacteria induces the production of cytokines and chemokines by the gingival epithelium
Analysis of proliferative activity in oral gingival epithelium
in immunosuppressive medication induced gingival overgrowth.
Total 32 samples of reconstituted buccal and gingival epithelium
were used in this study.
In the oral cavity, stem cells generate all the structures involved in dental hygiene therapy, including enamel, dentin, cementum, gingival epithelium
and periodontal ligament.
Interpretation & conclusions: The presence of CD 34 positive cells in gingiva in stromal, paravascular location, and basal layer of the gingival epithelium
and connective tissue areas were measured using image-analysis software (Sigma Scan[R]; Mocha; Jandel Scientific, San Rafael, CA, USA).
The junctional epithelium is reduced and the attached gingival epithelium
was thinner with small cells (Figs.
The other presentations include a so-called mural form (an indolent odontogenic cyst with mural SOT-like proliferations originating from the cyst lining or mural odontogenic epithelial rests) and a rare, extraosseous type (thought to arise from the overlying gingival epithelium
, similar to peripheral ameloblastoma).
2) Drug induced gingival overgrowth may be due to hyperplasia of gingival epithelium
or of submucosal connective tissue or of both, the major drugs that causes gingival hyperplasia are phenytoin (anti-convulsant), cyclosporine (immunosuppressant) and nifedipine and amlodipine (calcium channel blockers).