Therefore, porcine ES-like cells could differentiate into cells of three germ layers
and demonstrated their ability to differentiation in vitro.
The results showed that our cell lines expressed pluripotent markers, had normal karyotypes, and retained the potential to differentiate into the three germ layers
under in vitro conditions.
the mesodermal germ layer
surrounding the roots of the teeth) and in endosteal fibrous tissue.
Depending on the culture conditions, ES cells can either continue to grow in a pattern of prolonged self-renewal, or differentiate into derivatives of all three embryonic germ layers
(Thomson et al.
In contrast, the hpSCs developed by ISCO are derived from unfertilized eggs ("oocytes") that have been shown in peer-reviewed journals to exhibit unlimited proliferation potential and are pluripotent (can become cells from all three germ layers
that form a human being).
In addition, when cultured in the appropriate conditions, they can acquire pluripotency and differentiate into derivatives of the three embryonic germ layers
(Guan et al.
The data also demonstrate that therapeutically reprogrammed germ-line stem cells injected into mouse blastocysts give rise to all three germ layers
in the murine embryo, substantiating the finding that the cells are pluripotent.
Spheres are made up primarily of pluripotential progenitor cells that are capable of differentiating into cell types from the three germ layers
The stem cells were genetically normal and differentiated into cell types of all three germ layers
of the body, including blood cells, neurons, heart cells, cartilage, and other cell types of potentially therapeutic significance.
They consist of tissue from all three embryonic germ layers
The ectodermal dysplasias are a group of genetic disorders that affect the development of ectodermal tissues, the outermost tissues of the germ layers
of the human embryo.