It is expected that within the next few years, the genetic etiology
of RA will be substantially resolved by the repeated use of GWAS for populations worldwide and the meta-analysis of these studies.
4% (6, 7) didanosine, metronidazole, tamoxifen Trauma, post-ERCP, alpha-1- antitrypsin deficiency, infection Cystic fibrosis transmembrane conductance Typically only patients Genetic regulator (CFTR); cationic <25 years are tested for trypsinogen gene; serine a genetic etiology
(8-12) protease inhibitor, Kunitz type 1 (SPINT1) Category Details Proposed mechanisms Mechanical obstruction of ampulla of Vater and reflux of pancreatic enzymes Proposed mechanism: Toxic ethanol increases synthesis of lysosome and enzyme (2) Triglyceride levels >1000 mg/dL (4, 5); hypercalce- Metabolic mia proposed mechanism: induction of trypsinogen (3) Infectious agents: mumps, coxsackievirus, hepatitis B, Mycoplasma sp.
A possible genetic etiology
was implicated in fewer than 2% of cases.
Currently, there are >150 distinct conditions described as skeletal dysplasias, and each of these disorders is believed to have a unique genetic etiology
Fletcher, 1992; Olson, Rack, Conners, DeFries, & Fulker, 1991; Pennington, Gilger, Olson, & DeFries, 1992; Stevenson, 1991, 1992) failed to provide strong evidence that indicators of genetic etiology
were correlated with degree of aptitude-achievement discrepancy.
s confession to Ellis: family heredity and personal childhood experience are sufficient evidence to support genetic etiology
Evidence for a genetic etiology
in hyperactivity in children.