(GV) is a typically self-limited adverse event following vaccination (incidence 23.
An immunoglobulin containing antivaccinia antibody for the treatment and/or modification of serious complications of smallpox vaccination, including eczema vaccinatum, progressive vaccinia, severe generalized vaccinia
, and vaccinia infections in people who have skin conditions, such as burns, impetigo, or varicella zoster.
VIGIV might be used in cases of generalized vaccinia
, eczema vaccinatum or progressive vaccinia.
Some other well-documented complications of smallpox vaccination that date back to the era of routine smallpox vaccination include generalized vaccinia
, eczema vaccinatum, postvaccinial encephalitis, inadvertent inoculation, fetal vaccinia, and death.
31, 2003 Suspected Probable Confirmed Myocarditis or pericarditis 16 5 Inadvertent inoculation, nonocular 11 9 Ocular vaccinia 1 2 Generalized vaccinia
2 1 Postvaccinial encephalitis or 1 encephalomyelitis Note: Based on survillance data on 39,213 vaccinated civilian health care and public health workers.