To make this exercise more investigative, students can develop hypotheses based upon their knowledge about the chromosomal theory of inheritance, gene linkage
, and crossing over (Brooker, 2005) before they count the F2 generation.
The phenotypes are difficult to define, although recently there has been a huge increase in mapping of Mendelian as well as complex traits using two methods: gene linkage
, which can examine the entire genome, and genetic association, which starts with a candidate gene or a set of genes.
makes for more practical breeding strategies.
The gene linkage
test is the best way to identify people who have the gene but do not yet have cysts.
They followed the patterns of inheritance through several generations, developing a genome-wide gene linkage