Table 26: French Long-term Projections for Gene Amplification
Technologies by Segment - Polymerase Chain Reaction (PCR) and Other Gene Amplification
Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2011 through 2015 (includes corresponding Graph/Chart) III-24
HER-2/neu gene amplification
was detected on homogeneous DNA solution extracted from tumor piece, including the Southern blot technique, the dot-blot, and more recently the quantitative polymerase chain reaction.
It is apparent that the detection and quantitation of HER2 protein overexpression and gene amplification
has become an essential component during the diagnosis of GGEAC in order to predict response to existing and forthcoming anti-HER2 agents, which are now regarded as standard of care for HER2-positive GGEAC.
The relative advantages and disadvantages of the gene amplification
and the protein overexpression assays are summarized in Table 2.
of isolates gene amplification
isolates restriction analysis M.
Additionally, fixed cells were hybridized with an hTERC region-specific FISH probe to determine gene amplification
FISH evaluation: Of the 175 cases tested for HER2 gene amplification
, 108 cases (61.
Table 12: US 10-Year Perspective for Gene Amplification
The researchers used gene amplification
techniques to detect specific mutations in the gene coding for the enzyme glucocerebrosidase.
HER-2/neu gene copy number quantifed by real-time PCR: comparison of gene amplification
, heterorygosity, and immunohistochemical status in breast cancer tissue.
Contract award: provision of automated gene amplification
and quantification for bacteriology and virology laboratories at the university hospital of tours.
Restriction isotyping of human apolipoprotein E by gene amplification
and cleavage with Hhal.
5,6] Cyclin D1 gene amplification
is thought to be an important oncogenic event in many types of tumors, including esophageal carcinosarcoma.
Their method relies on a molecular copying process called polymerase chain reaction (PCR) gene amplification
, which has been steadily changing the face of molecular biology since it was developed at Cetus three years ago.
The test runs on the company's proprietary CellOptics([R]) platform, featuring the Ikoniscope([R]), a proprietary high-throughput, digital microscope, and provides "walk-away" automated testing of the HER2 gene to provide an early and accurate indication for gene amplification