Marx et al (2) studied HercepTest in gastric cardia
and noncardia tumors using the modified scoring criteria by Hofmann et al (23) and found that all (22 of 22) cases that showed strong (3+) staining for HER2 by immunohistochemistry and 5 of 6 cases with moderate staining were also positive for HER2 amplification by FISH, whereas none (0 of 138) of the cases with weak to absent staining were positive for gene amplification.
In total, 117 patients developed high-grade dysplasia or cancer of the esophagus or gastric cardia
, including 70 adenocarcinomas or unspecified cancers of the esophagus, 10 adenocarcinomas of the gastric cardia
, and 37 cases of esophageal high-grade dysplasia, the authors wrote.
Paragastric herniation of the gastric cardia
alongside the stomal segment is a rare complication (Figure 19) that may be caused by a band position anomaly.
The scope must be of adequate length to allow for a retroflexed view of the gastric cardia
and gastroesophageal junction; therefore, the scope should extend at least 60 cm, and perhaps 65 cm.
Diets with the highest content of cereal fiber are associated with a significantly lower risk for gastric cardia
adenocarcinoma, reported Dr.
This examination revealed inflammation of the distal esophagus and mild erythema of the gastric cardia
and antrum, as well as erythema of the duodenal bulb and descending duodenum.
However, maladies such as gastroesophageal reflux disease, Barrett's esophagus [an ulcerlike disease in the esophagus], and cancers of the lower esophagus and gastric cardia
[upper stomach] have been dramatically and progressively increasing.
The case records of 196 plan members diagnosed with adenocarcinomas of the esophagus and gastric cardia
from 1986 to 1992 were compared with the case records of 196 other members matched for membership at time of diagnosis, sex, year of birth, and duration of membership.
A physician endoscopically delivers controlled radiofrequency (RF) energy to the lower esophageal sphincter (LES) muscle and gastric cardia
to create thermal lesions.
Stretta is a minimally invasive, outpatient treatment for GERD that involves delivery of RF energy to the LES and gastric cardia
Epidemiologic studies have identified an additional distinct biologic group, so-called proximal gastric cancer, which combines tumors of gastric cardia
, GEJ, and distal esophagus based on their biologic similarities.
However, the study further revealed that their findings lacked explanation regarding the rising incidence of these tumours, specifically esophageal adenocarcinoma (EAC) and gastric cardia
adenocarcinoma (GCA), a cancer of the upper stomach area, where it joins the esophagus.
The procedure, which allows endoscopic visualization of the aerodigestive tract from the nasal vestibule to the gastric cardia
, is currently limited to a small number of U.
The risks of cancer of the gastric cardia
, liver, pancreas, and kidney and non-Hodgkin lymphoma were not significantly increased.
Rising incidence of adenocarcinoma of the esophagus and gastric cardia