Rs4979462, which is located in the nuclear factor 1 (NF-1)-related gene expression enhancer of tumor necrosis factor superfamily member 15 (TNFSF15), which is a PBC susceptibility gene in the Japanese population, was identified as a functional disease
susceptible variant using in silico and in vitro functional analyses.
They cover general topics like its history, the normal and abnormal development of the nervous system, examination, pediatric neurosurgery in developing countries, and ethics, and the epidemiology, clinical presentation, imaging, treatment, complications, and other aspects of congenital and developmental cerebral and spine disorders, neoplasms, trauma, cerebrovascular disease, functional disease
, and infectious disorders, as well as neuroanesthesia.
Even patients who are found to have minor erosions, a hiatal hernia or gastritis at endoscopy often have functional disease
, as these endoscopic findings are also common in the asymptomatic population.