fluorouracil


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  • noun

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an antimetabolite used to treat certain cancers

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References in periodicals archive ?
Phase II multi-institutional randomized trial of docetaxel plus cisplatin with or without fluorouracil in patients with untreated, advanced gastric, or gastroesophageal adenocarcinoma.
At 6 months, the mean number of AKs per participant had dropped to 3 in the fluorouracil group (a 73% reduction from baseline) vs.
Phase III study of weekly high dose infusional fluorouracil plus folinic acid with or without irinotecan in patients with metastatic colorectal cancer: European Organisation for Research and Treatment of Cancer Gastrointestinal Group Study 40986.
5% fluorouracil, and 2% received topical treatment with a different fluoro-uracil-strength formulation.
Contract notice: Delivery of two medicinal products for the treatment of cancer - cisplatin and fluorouracil.
Mylan also has acquired a license to manufacture and market Fluorouracil 5% USP cream as the exclusive authorized generic to Valeant's Efudex[sup.
Multicentre phase II study of Nordic fluorouracil and folinic acid bolus schedule combined with oxaliplatin as first-line treatment of metastatic colorectal cancer.
Oral capecitabine was associated with equivalent disease-free survival but greater safety than intravenous bolus fluorouracil plus leucovorin as an adjuvant treatment for stage III colon cancer, reported Chris Twelves, M.
In the first study, researchers in the National Surgical Adjuvant Breast and Bowel Project (NSABP) studied 679 node-negative patients, finding that women given chemotherapy -- a combination of methotrexate and fluorouracil - had an 80 percent disease-free survival rate four years later, compared with 71 percent of controls.
Food and Drug Administration for its Abbreviated New Drug Application ("ANDA") for Fluorouracil Topical Cream USP, 5% ("fluorouracil cream").
Oxaliplatin, fluorouracil, and leucovorin for patients with unresectable liver-only metastases from colorectal cancer: a North Central Cancer Treatment Group phase II study.
Valeant Pharmaceuticals (NYSE:VRX) today announced that the Food and Drug Administration (the FDA) has entered an administrative order "in the public interest" to stay the approval of generic fluorouracil cream 5% until May 30, 2008 "because there are outstanding questions regarding this approval that the Agency must consider.
Such a study has been performed by the UK Fluorouracil, Oxaliplatin and CPT-11 (irinotecan), Use and Sequencing (FOCUS) II investigators for a fluoropyrimidine [+ or -] oxaliplatin and demonstrated a limited advantage of oxaliplatin-based combination therapy in elderly patients [19].
24 /PRNewswire-FirstCall/ -- Sanofi-aventis announced today that results of two clinical studies demonstrating that Taxotere(R) (docetaxel) Injection Concentrate, when added to cisplatin and 5- fluorouracil for induction therapy, significantly improved overall survival (OS) in patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN) are published in the October 25 issue of the New England Journal of Medicine (NEJM).
Two new additions to chemotherapy regimens for colorectal cancer--bevacizumab added to irinotecan, fluorouracil, and leucovorin; and oxaliplatin added to fluorouracil and leucovorin--improved overall or disease-free survival, according to two multicenter, randomized trials.