(purity [greater than or equal to] 98%), Calcofluor-White and 2,7-dichlorofluorescein diacetate (DCFH-DA) were purchased from Sigma-Aldrich Co, St Louis, MO, USA.
The most commonly used antifungal agents are fluconazole
and amphotericin B deoxycholate because other drugs have extremely low urine concentrations.
301 The potential reasons for a relapse include IRIS, inadequate secondary fluconazole
prophylaxis, raised ICP despite fungal clearance or, uncommonly, fluconazole
For 1 isolate that was resistant to fluconazole
(MIC 128 mg/L), MICs for voriconazole and posaconazole were both below the EB (0.
Comparison of the early fungicidal activity of high-dose fluconazole
, voriconazole, and flucytosine as second-line drugs given in combination with amphotericin B for the treatment of HIV-associated cryptococcal meningitis.
The purpose of the present study was to investigate the disposition of fluconazole
in cockatiels after single oral dose administration and to determine if therapeutic plasma concentrations could be safely achieved by providing medicated water.
The diagnosis in these case reports has been made by exclusion and probability scoring, as drug levels of fluconazole
could not be done.
parapsilosis) revealed that 21 isolates (70%) were susceptible (MIC, < 8 [micro]g/ ml) to fluconazole
while 9 (30%) were susceptible-dose dependent (S-DD, MIC 16-32 [micro]g/ml).
and voriconazole are both available as intravenous and oral formulations and have favorable safety profiles.
Rhodotorula species are consistently resistant to fluconazole
In these studies, NOXAFIL demonstrated an adverse event profile comparable to fluconazole
If you see a health care professional, he or she may prescribe a single dose of oral fluconazole
(Diflucan) or a generic equivalent, although this treatment is not recommended during pregnancy.
Pfizer says Eraxis is the only antifungal that has shown improved efficacy versus fluconazole
in a pivotal candidemia clinical trial.
of candidemia had improved efficacy versus those taking fluconazole
A partial list of these medications includes ciprofloxacin, erythropoietin, lamivudine (for the treatment of hepatitis B), fluconazole
, ketoconazole, itraconazole, ganciclovir (to treat CMV), ribavirin and interferon (to treat hepatitis C), rifabutin (to treat MAI), and famciclovir (to treat Herpes Simplex).