Kuros has two biomaterial technology platforms, one based on fibrin
sealants and the other based on its own proprietary synthetic technology that can mimic fibrin
in many of its attributes.
These data are the first to show idarucizumab reverses dabigatran-induced inhibition of wound-site fibrin
formation, which plays a key role in the blood clotting mechanism, said Joanne van Ryn, Ph.
The transition was particularly successful in the fibrin
-collagen mixes, which saw as many as half of the colonies converting to heart muscle.
offers an alternative biomaterial that is simple and inexpensive to prepare.
Conclusion: The use of fibrin
sealant and tissue adhesive was beneficial, as they reduced the level of factor concentrates used for replacement therapy and resulted in rapid hemostasis at the surgical site, facilitating the ability to perform serial surgical procedures concurrently.
The diagnosis of dysfibrinogenemia is dependent on laboratory investigation, traditionally using tests of fibrin
clot formation; the TT and RT are the screening tests, and the fibrinogen clotting activity-antigen ratio is the confirmatory test.
But beyond this essential work, fibrin
can also cause heart attack, stroke and tissue damage by forming clots that block blood vessels.
The parties have entered into a Distribution Agreement whereby Angiotech is granted non-exclusive, world-wide distribution rights to Haemacure's fibrin
sealant product candidate in selected surgical indications.
Haemacure plans on having a first patient undergo surgery in the planned pivotal Phase II/Phase III clinical trials for its human fibrin
sealant Hemaseel(R)HMN during the first quarter of calendar 2009.
Per the agreement, Baxter's fibrin
sealant will be combined with Spinal Restoration's proprietary technologies to create the minimally invasive Biostat Disc Augmentation System, which will be developed and tested for the treatment of intervertebral disc degeneration.
TAMPA -- The use of an autologous platelet-rich fibrin
matrix appears to safely and conveniently accelerate the healing of diabetic foot ulcers, Christine Gosch, D.
measured how far individual fibrin
fibers can stretch.
Clots consist of a mesh of fibrin
fibres, each roughly 1,000 times thinner than a human hair.
The introduction of fibrin
sealants has brought into question the necessity of routinely placing suction drains.
These include the highest currently known fibrin