MRI-guided vacuum-assisted breast biopsy is a reliable method for diagnosis of MRI-only lesions with 11% false-negative rate
The difference of reporting categories between daily practice and the PAP-Edu program may affect the false-negative rate
of AIS in the PAP-Edu program.
It provides the basis for our estimate of the false-negative rate
On the downside, the procedure is highly operator dependent, requires special training by a pathologist and is associated with an appreciable false-negative rate
There is a high false-negative rate
in this situation , This has been contradicted by a study performed in Cremona, Italy, where researchers were able to show that neoadjuvant chemotherapy does not alter the location of sentinel lymph nodes and they demonstrated a high pick-up rate before and after neoadjuvant chemotherapy , A meta-analysis in support of SLNB post neoadjuvant therapy on 1273 patients from 21 small studies showed an overall SLN detection rate of 90%, sensitivity 88%, specificity 100%, and false-negative rate
of 12% , This compares very well with three meta-analyses of SLNB in patients who had not received neoadjuvant chemotherapy [25,26], with a highest detection rate of 96% and a false-negative rate
of 7% in one of the studies .
Sixty-two percent of the men with a negative biopsy reported being "a lot" reassured by the result, despite the 10% false-negative rate
associated with biopsy.
Figure 1 shows that four quantitative characteristics [sensitivity (Se), specificity (Sp), positive predictive value (PPV), and negative predictive value (NPV)] are defined by two properties of the screening method (the false-positive rate, or, and the false-negative rate
, [3) and by a property of the danger being assessed, the frequency of true hazards, P[H], where H is a true hazard.
A false-negative rate
of five percent or less was used as the performance criterion.
Over the past few years, physicians have been moving toward use of the ThinPrep Pap test for primary cervical-cancer screening because of its decreased false-negative rate
But labs measured in a nationwide proficiency test last year had a much lower false-negative rate
of about 5 percent.
3) Tiffet O et al; "Combining radioisotopic and blue-dye technique does not improve the false-negative rate
in sentinel lymph node mapping for colorectal cancer.
It has been previously reported that 1% of HSIL slides in 2006-2007 PAP-PT were undercalled as negative by the participants, and that this was slightly lower than the false-negative rate
The false-negative rate
of Pap smear cytology is 45%.
So in essence, we're reducing the false-negative rate
from 26% down to 4%," he said.
Therefore, small size and low number of tumours could potentially account for the high false-negative rate
(38%) seen in this study when accessing NMP22's ability to detect early carcinogenesis or subclinical recurrences.