To further explore DNA methylation changes in infants related to maternal smoking during pregnancy, we performed an epigenome-wide association study (EWAS) using whole blood from 889 infants in the Norway Facial Clefts
Study (NCL), including 287 whose mothers smoked during the first trimester.
The results of this study are consistent with those reported by Maris (2000) suggesting that despite initial negative reactions parents are able to reorganise their thoughts and feelings and develop acceptance of their infant with a facial cleft
, because of the support provided by the Cleft Service.
Regional cleft networks offer antenatal support to parents who are found to be expecting a child with a facial cleft
at their 20-week anomaly scan
Using data from the Norway Facial Clefts
Study (NCL), a population-based case-control study, the investigators assessed associations between maternal amalgam fillings and two categories of facial clefts
that appear to have different etiologies: cleft lip with or without cleft palate, and isolated cleft palate.
Research: This population-based study was conducted in Norway, which has one of the highest rates of facial clefts
in Europe and does not allow foods to be fortified with folic acid.
Viet is a two-year-old boy who was born with one of the world's rarest facial deformities which comprises a cleft palate and bilateral facial clefts
A study found that taking folic acid - already hailed for cutting the risk of conditions such as spina bifida - had more of an effect on facial clefts
than previously thought.
THE BABY WITH A NEW FACE: EXTRAORDINARY PEOPLE Five, 9pm Vietnamese two-year-old boy Viet was born with one of the world's rarest facial deformities which compromises of a cleft palate and bilateral facial clefts
Case-control data also suggest an association between smoking during pregnancy and facial clefts
, at least in certain subgroups.
The team offers sub-specialized, multi-disciplinary and individualized care of all aspects of cleft lip and palate, orthognathic surgery, craniosynostosis, craniofacial microsomia, facial clefts
, resonance disorders and pediatric facial trauma.