Rather, optimal glycaemic control, through adjustments of exogenous insulin
replacement therapy based on measured HbA1c levels, appears to be a consistent and independent predictor of an increase in body weight.
Insulin antibodies and surreptitious use of exogenous insulin
can produce inappropriately high concentrations of insulin during hypoglycemia.
Conclusion: Exogenous insulin
produces significant effects on the placental, fetal and maternal outcomes in patients with GDM KEY WORDS: Gestational diabetes, Insulin, Placenta, Gross morphology, Fetal outcome, Maternal outcome.
While type 1 can only be treated with exogenous insulin
, this can be provided with syringes, insulin pens, and insulin pumps.
Those conducting this research anticipate that the system they are developing will be less costly, more effective and more acceptable to patients in improving glycaemic control than exogenous insulin
Type I diabetes is treated with exogenous insulin
It has become clear during the past 20 years that the clinical implications of insulin resistance reach far beyond that of a diabetic patient requiring excessive quantities of exogenous insulin
similarly stimulates appetite, and the tighter the glucose control, the greater the effect of insulin on appetite and weight gain.
Types of exogenous insulin
Insulin comes in a variety of types: rapid, short, intermediate or Long-acting; single or biphasic mixtures; and animal, human or analogue forms.
The clinical spectrum of insulin resistance is quite broad, and may include those patients with diabetes mellitus (type 2) who require no insulin and who continue to have hyperglycemia despite large doses of exogenous insulin
and patients who maintain near normal blood glucose levels though marked elevations in endogenous insulin secretion.
We studied the effect of CEx1-3 on sensitivity to exogenous insulin
in insulin-resistant HepG2 ceils and normal cells in vitro to see whether the improvement of glucose disposal in vivo was associated with enhancement of insulin action in hepatic cells.
may result in an inflammatory or immunologic reaction to the insulin, the vehicle or a contaminant in the vehicle (6), (7)
Basal insulin administered to a hospitalized patient should provide the amount of exogenous insulin
per unit of time necessary to prevent gluconeogenesis and ketogenesis (Clement et al.
Early studies indicate that metformin, the most common medication for patients with type 2 diabetes, may be associated with a lower cancer risk, while exogenous insulin
(insulin not manufactured in the body) may be associated with a higher risk.
1 million American adults with type 1 diabetes of either the classic type or latent autoimmune diabetes of adults (LADA), a group whose absolute need for exogenous insulin
is somewhere between that of classic childhood-onset type 1 diabetes and adult type 2 disease.