Insulin antibodies and surreptitious use of exogenous insulin
can produce inappropriately high concentrations of insulin during hypoglycemia.
Subjects with LADA often require exogenous insulin
administration for control of their diabetes after failing to respond to oral anti-diabetic drugs.
All T1DM is treated with exogenous insulin
and, as the incidence of type 2 increases, more of this group will also be using insulin therapy.
Patients are diabetic, predominantly type 1, on exogenous insulin
8) Exogenous insulin
is given to all patients with type 1 DM, some patients with type 2 diabetes, if required, and some pregnant women.
As time passes, the pancreatic islets in the liver will take up new blood supply, and the patient's requirement of exogenous insulin
is expected to decrease, facilitating diabetes management and preventing the onset of complications of the disease, and ultimately improving his quality of life.
frequently fails to achieve optimal glucose control even when intensive regimens are used.
15-19) The risk of hypoglycemia increases with absolute or relative insulin excess (caused by exogenous insulin
or agents that increase insulin secretion) or compromised glucose regulation.
Furthermore, when these individuals learned to make better reactions to life's circumstances, the personality who needed exogenous insulin
, needed less of it.
Hyperglycemic treatment with exogenous insulin
alters the metabolic abnormalities seen in hyperglycemia (American Association of Clinical Endocrinologists [AACE], 2003).
Therefore extensive investigations are being conducted to achieve successful control of blood glucose by using delivery devices and systems for the delivery of exogenous insulin
While careful glucose control is essential for both types of patients, the distinction is important because most patients with gestational diabetes can be well managed with a 2,000-2,400 calorie American Diabetes Association diet without exogenous insulin
Primary endpoints are proposed to be safety of monocyte derived pancreatic-like islet cell transplantation and insulin independence or reduction in exogenous insulin
requirements at one year post initial infusion.
If the hypoglycemia is caused by exogenous insulin
, however, laboratory results typically will show that the cosecreted C-peptide is low.
People with Type 1 diabetes generally develop the condition during childhood or as young adults and they will always require exogenous insulin
ie insulin not produced by their own pancreas.