Solvay Seiyaku and Eisai work in tandem to bring SA-001 as a new treatment option to contribute to the treatment of patients with pancreatic exocrine
insufficiency and to improving their quality of life.
Eighty to 95% of the pancreatic parenchyma is composed of acinar cells, which are dedicated to the exocrine
functions of producing and secreting digestive enzymes, such as trypsinogen, lipase.
Liprotamase - which contains lipase, protease, and amylase and is available in capsule form and in one strength only - is being reviewed by the FDA for the treatment for patients with exocrine
pancreatic insufficiency (EPI) caused by cystic fibrosis (CF), chronic pancreatitis (CP), pancreatectomy, or other conditions that limit or impair function of the pancreas; this indication was proposed by the manufacturer, Alnara Pharmaceuticals.
under FDA review for the treatment of exocrine
pancreatic insufficiency (EPI).
altiparanae was the intrahepatic exocrine
pancreatic tissue associated to afferent vessels.
World Health Organization: institutional histological classification or tumours histological typing of tumours of the exocrine
pancreas 2nd ed.
component synthesizes and secretes enzymes into the duodenum that are essential for digestion in the intestine.
It is uncommon and distinct from what is generally referred to as pancreatic cancer or pancreatic exocrine
Larvae were examined for the location of exocrine
gland openings which is a characteristic of this insect family (Weatherson et al.
alpha]-Amylase activity examination in duodenum fluids of exocrine
pancreas: The [alpha]-amylase activity of duodenal fluid secreted from the exocrine
gland of the pancreas was measured using an EnzyChrom[TM] [alpha]-amylase Assay Kit (ECAM-100, BioAssay Systems, USA).
Broadly speaking, two cellular compartments are important in a normal pancreas, endocrine cells, which produce hormones including insulin, and exocrine
cells - acinar and ductal-which make and secrete digestive enzymes.
A delayed-release capsule formulation of pancrelipase, which will be marketed as Ultresa, has been approved for the treatment of exocrine
pancreatic insufficiency caused by cystic fibrosis or other conditions in children and adults.
The syndrome - unrelated to the cancer he has previously battled against - affects the exocrine
glands that produce tears and saliva and is a long-standing problem of McPhail's.
Pancreaticoduodenectomy in a patient with agenesis of dorsal pancreas would entail removal of all pancreatic tissue and hence result in postoperative endocrine and exocrine
insufficiency requiring lifelong insulin and enzyme replacement therapy.
Postmortem examination demonstrated exocrine
pancreatic degeneration, necrosis, and atrophy.