The most common adverse events in patients receiving Avastin were asthenia, pain, abdominal pain, headache, hypertension, diarrhea, nausea, vomiting, anorexia, stomatitis, constipation, upper respiratory infection, epistaxis, dyspnea, exfoliative dermatitis
Adverse events linked to ephedra include increased blood pressure, heart ailments, strokes, dizziness, psychosis, headache, exfoliative dermatitis
, insomnia, and uterine contractions.
We present a case of phenytoin-induced cholestatic hepatotoxicity in a 47-year-old woman who had exfoliative dermatitis
, an increase in liver enzymes with a cholestatic pattern, and eosinophilia after 25 days of phenytoin therapy.
The labeling changes for Bextra include a warning regarding the risk of serious skin reactions, including Stevens-Johnson syndrome, exfoliative dermatitis
, toxic epidermal necrolysis, and erythema multi-forme.
Serious skin reactions such as exfoliative dermatitis
, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal: Discontinue Dyloject if rash or other signs of local skin reaction occur.