Today's FLAME study results provide clear further evidence that Ultibro Breezhaler is more effective than Seretide in reducing COPD exacerbations
, events linked to significant patient suffering and more rapid progression of the disease," said Vasant Narasimhan, Global Head of Development, Novartis Pharmaceuticals.
When stratified by genotype, there were no significant differences in hazard ratios for time to first exacerbation
, mean number of exacerbations
, or lung function at 6, 12, or 18 months.
Other risk factors for exacerbation
included previous asthma exacerbations
For high-risk patients, this higher dose of NAC at 600 mg twice daily significantly reduced the exacerbation
frequency at 8 and 12 months, a prolonged amount of time until the first exacerbation
and an increased probability of having no exacerbations
at 1 year, compared with placebo.
roflumilast) significantly reduced exacerbations
and hospitalizations in patients with severe chronic obstructive pulmonary disease (COPD), who are at risk of frequent and severe exacerbations
despite already receiving inhalation therapy with ICS/LABA combinations or triple (LAMA/ICS/LABA) therapy.
There is limited or suggestive evidence of an association between dust mite allergen exposure and exacerbations
of asthma in children not sensitized to dust mites and in adults, whether sensitized or nonsensitized.
This study suggests that winter consumption of a yang-warming, kidney essence-replenishing herbal paste may help to prevent cold-related asthma exacerbations
throughout the subsequent year.
1], dyspnoea, and quality of life, with similar trends in reduction of exacerbations
in patients with COPD.
It is again clear for COPD patients that these exacerbations
are really hard to treat" and prevent, Janssens told.
The results demonstrated positive trends in lung function as measured by FEV1 (forced expiratory volume in one second) and in the secondary outcome measure, rate of pulmonary exacerbations
The researchers found that vitamin D supplementation did not reduce the number of acute exacerbations
of COPD nor improve lung function.
DENVER - Exacerbations
of chronic obstructive pulmonary disease show distinctly different temporal patterns of onset and resolution, which could affect treatment and prognosis, researchers reported.
In the process, asthma patients should understand the characteristics of exacerbations
, and have a plan to treat and confront exacerbations
052) and of moderate and severe exacerbations
Background: Frequent exacerbations
are associated with a faster decline in [FEV.