ethacrynic acid


Also found in: Dictionary, Medical, Wikipedia.
  • noun

Synonyms for ethacrynic acid

diuretic (trade name Edecrin) used to treat edema

References in periodicals archive ?
Tetracycline Antiseptics Acetic acid Alcohol Chlorhexidine Cresylate Gentian violet Vehicles Benzalkonium chloride Polyethylene glycol Propylene glycol Salicylates Nonsteroidal anti-inflammatory drugs Quinine Chemotherapeutic drugs Carboplatinum Cisplatinum Vinblastine Vincristine Loop diuretics Ethacrynic acid Furosemide Table 2 Agents that protect against ototoxicity Alpha lipoic acid Antioxidants Calcium Fosfomycin Glutathione Iron chelators
In addition, the preclinical studies continue to support our belief that ethacrynic acid and certain related molecules might provide a new generation of glaucoma therapy based on a novel mechanism of action that reduces pressure by increasing fluid outflow from the eye.
Telor has developed an eyedrop formulation of TEKRON using new excipients with the active ingredient ethacrynic acid.
Rather than proceeding with further clinical trials of the current formulation, we plan to make a decision in the near future regarding the most prudent course for development of an ethacrynic acid analog or an alternative formulation," said Stephen J.
Riggi also noted that both the Phase IIa study and the effort to develop analogs of ethacrynic acid are part of a broad program to develop new anti-glaucoma products that control intraocular pressure by increasing fluid outflow from the eye.
Telor has an exclusive worldwide license from the Massachusetts Eye and Ear Infirmary to patents issued in the United States, Canada, Australia and Europe and pending elsewhere covering the pharmaceutical use of ethacrynic acid to lower intraocular pressure by increasing the outflow of fluid from the eye.
Important Information About Ethacrynate Sodium for Injection All diuretics, including ethacrynic acid, are contraindicated in anuria.
Stock solutions of the inhibitors, including ethacrynic acid, bromodulfalein, diethyl maleate, tetraethylthiuram disulfide, and curcumin were prepared in ethanol and diluted with Tris-HCl (50 mM, pH 7.
The adult possessed the highest values toward ethacrynic acid.
Exposure of NSC34 cells to Ethacrynic Acid (EA) or L-Buthionine Sulfoximine (BSO) dramatically reduced the cellular GSH level, and was accompanied by increased production of reactive oxygen species (ROS) measured by the DCF fluorescent oxidation assay.
Abstract: Ethacrynic acid is a loop diuretic little used today because of its side-effect profile and the availability of multiple alternative agents.
Inhibition of glutathione-related enzymes and cytotoxicity of ethacrynic acid and cyclosporine.
Until recently, ethacrynic acid (Edecrin) was also on market, but now no longer available.
Simultaneous analysis of flunixin, naproxen, ethacrynic acid, indomethacin, phenylbutazone, mefenamic acid and thiosalicylic acid in plasma and urine by high-performance liquid chromatography and gas chromatography -mass spectrometry.
The drug in question, ethacrynic acid, has been approved by the Food and Drug Administration as a diuretic but not for the treatment of glaucoma.