The apoptotic and nonapoptotic nature of the terminal differentiation of erythroid cells
Although the rate-limiting step in non-erythroid cells
is the delta-aminolevulinate formation, in erythroid cells
, the rate-limiting step is acquisition of iron to mitochondria.
A stained cytospin made from the final cell suspension showed predominantly blast cells with multiple nucleoli and a moderate amount of blue cytoplasm as well as dysplastic erythroid cells
with markedly irregular nuclei containing 1 to 3 nucleoli.
Urotensin II is also an essential component of Ankaferd and represents the link between injured vascular endothelium, adhesive proteins and active erythroid cells
Abnormally spliced messenger RNA in erythroid cells
from patients with a+ thalassemia and monkey cells expressing a cloned [[beta].
Sixteen of 20 cases showed weak cytoplasmic staining in the erythroid cells
Bone marrow trephine biopsy was normocellular with 40% marrow cellularity, consisting of a patchy distribution of myeloid and erythroid cells
and normal numbers of nonclustered megakaryocytes, some of which had hypolobated nuclei.
This activity is called hematopoietic cell sparing, which refers to the absence of effect on the precursors of normal blood elements such as neutrophils, erythroid cells
Culture of fetal erythroid cells
from maternal peripheral blood.
Repair of a splicing defect in erythroid cells
from patients with b-thalassemia/ HbE disorder.
Isolation of fetal erythroid cells
from maternal blood based on expression of erythropoietin receptors.
Expression of major blood group antigens on human erythroid cells
in a two phase liquid culture system.
Caution should be taken with other approaches, such as gating on CD45+ cells, because mature nucleated bone marrow erythroid cells
(112) as well as some leukemic cells may be negative for this antigen (113-115).
Intriguingly, GST inhibitors are present in uremic plasma, and this could justify an overexpression of GST in erythroid cells
HPLC analysis of Hb was also performed in culture-grown erythroid cells
obtained from an Hb J Sardegna carrier.