MDAC was given in view of the long elimination half-life and enterohepatic circulation
If there is any disturbance in the enterohepatic circulation
of bile salts, it can decrease the relative concentration of bile salts in gallbladder and can lead to the formation of cholesterol stones (5,6).
We performed a pilot study to understand whether puerarin undergoes an efficient enterohepatic circulation
Partial diversion of the enterohepatic circulation
using BAS depletes the endogenous bile acid pool by approximately 40%, thus stimulating an increase in bile acid synthesis from cholesterol, which lowers low-density lipoprotein cholesterol (LDL-C) by 15 to 26%.
3) In the intestines, most bile acids are reabsorbed into the enterohepatic circulation
by the ileal bile acid transporter.
8) Evidence for an enterohepatic circulation
of inorganic iodine was observed for the first time.
Ezetimibe, a Schering-Plough drug, inhibits cholesterol absorption both from the gut and the enterohepatic circulation
The mammalian lignans, enterodiol and enterolactone, can be excreted directly in the feces, or after being absorbed in the gut, they enter the enterohepatic circulation
where they are conjugated with glucuronate, and then excreted in urine and bile [10,11].
Physicians should perform gastric ravage and administer repeated doses of activated charcoal to remove any unabsorbed Amanita and to interrupt the enterohepatic circulation
of the toxin (2,4,5).