Meloxicam is a nonsteroidal anti-inflammatory drug of the enolic
acid class of compounds used in the treatment of rheumatoid arthritis and osteoarthritis.
On TLC the compound gave a violet spot with p-nitroaniline spray reagent indicating that it is either phenolic or enolic
, a dark brown colour with anisaldehyde spray reagent and a bright yellow colour with, 2,4 DNP spray reagent, suggesting that a carbonyl group might be present.
Humified material is often a stronger sorbent due to the presence of oxygen-containing functional groups such as -COOH, phenolic, aliphatic, enolic
, -OH, and C=O.
phenylpyruvic acid-2-0-(3-D-glucoside (PPAG) was isolated from rooibos (purity Greater than 95% by HPLCand LC-MS)and supplied by the Post-Harvest & Wine Technology Division of the Agricultural Research Council of South Africa (ARC Infruitec-Nietvoorbij, Stellenbosch, South Africa).
Meloxicam is a NSAID in the group of the enolic
acids found to preferentially inhibit cyclooxygenase-2 (COX-2) rather than cyclo-oxygenase-1 (COX-1), the latter being responsible for physiologic processes such as renal and gastric mucosal protection.