Except in the patients with massively enlarged kidneys
, PD is a viable method of renal replacement therapy with a good outcome in PKD patients.
Controls either had no renal biopsy or a negative renal biopsy, no kidney imaging or no evidence of enlarged kidneys
, and did not have evidence in their medical record of nephrotic range proteinuria or serum creatinine elevation >2.
As her daughter was born with enlarged kidneys
, she has to take her to Cairo for tests and treatment every four to five months-- a far cry from the monthly treatment the girl used to receive in Iraq.
If a baby has the disease it is usually identified soon after birth when the enlarged kidneys
cause the abdomen to swell.
In the CT of the abdomen, a thickened wall of the colon ascendens, an enlarged caecum, slightly enlarged kidneys
, approximately 500 mL of ascites, and enhancement of the peritoneum were found.
This case was quite different from the classical picture in which patients with FMF usually have profound proteinuria, hypoalbuminemia, and symptomatic nephrotic syndrome along with normal-sized or enlarged kidneys
Kidney size was available in 181 cases; 69 cases (~38%) were associated with enlarged kidneys (8 of which had sizes 2 standard deviations above the mean for age), whereas in 38 cases (~20%) the kidneys were small for age.
Classic ARPKD presents in neonates with severe acute renal failure and symmetrically enlarged kidneys, dilated collecting ducts, and congenital hepatic fibrosis.
This is illustrated in the case of a 3-year-old boy (case 6) who presented with bilaterally enlarged kidneys interpreted as infiltrative masses" consistent with Wilms tumor (Figure 6, A).
They also had high blood pressure, shrunken livers and enlarged kidneys