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The glycan code of the endoplasmic reticulum: asparagine-linked carbohydrates as protein maturation and quality-control tags.
Endoplasmic reticulum: A system of folded membranes that loop back and forth, spreading throughout the cytoplasm and providing a large surface area for cell reactions.
Each oogonium had a large nucleus with chromatin, several mitochondria and the endoplasmic reticulum in the cytoplasm (Fig.
RBCC and Amarantus are currently wrapping up due diligence toward a potential joint venture agreement to develop and market MANF as a treatment for disorders associated with endoplasmic reticulum stress, including traumatic brain injury, Parkinson's disease, Alzheimer's disease and other afflictions.
We're incredibly proud of what we've done, and we can't wait to for a larger audience to get a taste of what Chatty Monks is about-particularly our Endoplasmic Reticulum IPA
The sigma-1 receptor is an endoplasmic reticulum (ER) integral membrane protein receptor is implicated in neurodegeneration, drug addiction, pain, amnesia, depression, Alzeimer s disease, stroke, retinal neural degeneration, HIV infection, and cancer.
It is overexpressed in the endoplasmic reticulum where it functions as a chaperone protein assisting in protein folding events (Pfaffenbach and Lee, 2011).
SREBPs are made and embedded in the membrane of the cellular compartment called the endoplasmic reticulum, or ER.
During her eight-minute presentation, Nirinjini Naidoo, PhD, University of Pennsylvania Perelman School of Medicine, Division of Sleep Medicine, summarized the studies and reviews she has published on the subject of endoplasmic reticulum stress (ER stress), sleep deprivation, and aging.
Purpose: We aimed to investigate the presence of antibodies (Anti-BIP) against binding immunoglobulin protein (BIP), an endoplasmic reticulum (ER) chaperone with immune modulator and anti-apoptotic effects in Hashimoto's thyroiditis (HT) patients
The 21 contributions in this volume review current understanding of the cell biology underlying protein-folding homeostasis in the endoplasmic reticulum, the mammalian endoplasmic reticulum-associated degradation system, and factors regulating the structure of the endoplasmic reticulum.
Previous studies in the investigators' laboratory showed that CYP2D6, a protein that is predominantly localized to cells' endoplasmic reticulum, was also targeted to their mitochondria.
The treatment with eurycomanone reduced the abundance expression of the lung cancer markers, heterogeneous nuclear ribonucleoprotein (hnRNP) A2/B1, p53 tumor suppressor protein and other cancer-associated genes including prohibitin (PHB), annexin 1 (ANX1) and endoplasmic reticulum protein 28 (ERp28) but not the house keeping genes.
of Pennsylvania School of Medicine) present 13 papers concentrating on three areas concerning age-related oxidative modification of neural functioning: the roles of reactive oxygen species and reactive nitrogen species in cellular biology; an overview of redox imbalance injury with effects on mitochondria, signaling, endoplasmic reticular functioning, and aging in general; and the roles that redox imbalances play in age-related susceptibility to disease and in the disease processes.
2+] entry (SOCE) following the depletion of endoplasmic reticulum (ER) [Ca.
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