Our study provides the proof-of-concept that a therapy aimed at repairing the endolymphatic sac
during embryonic development is sufficient to restore a lifetime of normal hearing and balance," Wangemann said.
The best diagnostic clues on imaging for an endolymphatic sac tumor include its characteristic location in addition to central calcified deposits and bone spicules on CT along with intratumoral high signal intensity on noncontrast T1 MRI evaluation (1-3).
Endolymphatic sac tumor and von Hippel-Lindau disease: imaging features.
In a description of the pathologic changes of an aggressive papillary tumor of the middle ear in an autopsy temporal bone, widespread deposits of tumor were found at inner ear sites, but no mention was made of involvement of the endolymphatic sac or duct.
Mutation of von Hippel-Lindau tumor suppressor gene in a sporadic endolymphatic sac tumor.
Final pathology confirmed that the tumor was an adenocarcinoma of endolymphatic sac origin.
13) Nearly a century later, Heffner correctly described the entity as a low-grade adenocarcinoma and recognized its origin as the endolymphatic sac.
22) During endolymphatic sac surgery, Huang used 1 mg/ml for 5 minutes.
In 1999, Yazawa et al published their experience with mitomycin C during endolymphatic sac surgery, and they reported no heating impairment or dizziness among 14 patients who had been followed for more than 6 months.
Similarly, vascular compression of the endolymphatic sac and duct has been shown to be associated with Meniere's symptomatology in the presence of anatomic variants such as jugular megabulb (6) and an anomalous vein of the vestibular aqueduct.
Patients 1 and 2 exhibited compression and erosion of the endolymphatic sac and duct by a jugular megabulb and a cholesterol granuloma, respectively.
As mentioned, endolymphatic sac
enhancement is one of those procedures, and we have done many of them.
4% had performed endolymphatic sac
surgery, and 72.
4) Surgery is reserved for patients who still do not respond; surgical procedures include endolymphatic sac
decompression, vestibular neurectomy, or labyrinthectomy.
3] Since then, however, Hicks and Wright reported that endolymphatic sac
(ELS) surgery in patients with contralateral hydrops is relatively safe, provides an excellent chance of eliminating or controlling vertigo and maintaining or improving hearing, and carries a low risk of surgical anacusis.