Rabs, a family of small GTPases, are key players in endocytosis
, recycling of cell surface molecules, identifying types of vesicles, and regulating the formation, movement, and fusion of vesicle membranes.
Some of the IPTP perturbed pathways included caveolar-mediated endocytosis
signaling and clathrin-mediated endocytosis
signaling, both of which are involved in insulin receptor and solute carrier family 2 (facilitated glucose transporter), member 4 (GLUT4) endocytosis
, respectively (Fagerholm et al.
Adaptor protein ARH is recruited to the plasma membrane by low density lipoprotein (LDL) binding and modulates endocytosis
of the LDL/LDL receptor complex in hepatocytes.
During feeding, the limited permeability of the adherens junctions helps to confine materials released from lysed algae to the space under the animal, where they are taken up into epithelial cells by endocytosis
It is involved in the formation of caveolae, endocytosis
, signal transduction, angiogenesis and other physiological process (Chidlow and Sessa, 2010).
takes place, adjuvants first exert their targeting mechanism by binding to antigens and the adjuvant-antigen complex is delivered to antigen-presenting cells (APCs) to form aggregates that are then engulfed by APCs to form endosomes (Cox and Coulter, 1997; Zamze et al.
It strongly suggests that the mechanism may be linked to the gentamicin accumulation in renal cortex through ultrafiltration, long half-life there (100 hours comparing to 30 minutes in the plasma), diffusion from the tubular lumen to the apical membranes of renal proximal tubular cells by Megalin-mediated endocytosis
precipitated the renal damage.
Therefore, a pH gradient is established and this gradient plays a vital role in view of the fact that endosomal/lysosomal devices are the key components in the internalization of polymeric nano particles through the process of endocytosis
Once the magnetic nanoparticles are entered into the cancer cells through endocytosis
they are heated with the help of an external localized and alternating magnetic field.
2]AR is subsequently redistributed to a coated pit and finally internalized in form of early endosomes by endocytosis
reported that DCs internalized exosomes via endocytosis
We performed an endocytosis
ability test to determine whether Dx affected functional alteration induced by 27OHChol on monocytic cells (Figure 3).
After exocytic release of transmitter, vesicles are retrieved by endocytosis
and refilled with transmitter to be reused for another round of neurotransmission (Fig.
Hepcidin controls iron flows by binding to ferroportin and causing its endocytosis
and proteolysis, thus closing the valve.
The study authors submit: "By reducing the energetic cost of membrane bending and fission, polyunsaturated [phospholipids] may help to support rapid endocytosis