manipulation

(redirected from endocrine manipulation)
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Synonyms for manipulation

exerting shrewd or devious influence especially for one's own advantage

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the action of touching with the hands (or the skillful use of the hands) or by the use of mechanical means

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References in periodicals archive ?
Biopsies of tumours from breast cancer patients who have relapsed while receiving treatment with an anti-oestrogen agent show a functional ER [23], while women who have become refractory to tamoxifen or non-steroidal AIs actually respond to further endocrine manipulation with the ER[alpha] downregulator fulvestrant [24,25], indicating that ER-mediated signalling remains functional.
This is supported by a recent clinical trial showing that women who have relapsed on an AI respond to more potent endocrine manipulation using the irreversible AI exemestane, or ER downregulation with fulvestrant [25].