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Epileptic encephalopathies are a diverse group of severe epilepsy disorders in which uncontrolled epileptic activity contributes to a progressive decline in cognitive and motor function.
Spongiform encephalopathies (SEs) are transmissible neurodegenerative diseases characterized by spongiform lesions and deposition of partially proteinase K-resistant prion protein ([PrP.
Rohwer, at the Cambridge Healthtech Institute's 10th Annual Transmissible Spongiform Encephalopathies Conference in Baltimore, MD.
Food and Drug Administration (FDA) has cleared the Investigational New Drug (IND) application for TUR-004 in the treatment of epileptic encephalopathies.
An alternative pretreatment procedure in animal transmissible spongiform encephalopathies diagnosis using PrPsc immunohistochemistry.
At the request of the Food and Drug Administration (FDA) Transmissible Spongiform Encephalopathies (TSEs) Advisory Committee, Pall Corporation (NYSE: PLL) today presented the latest research results on its prion technology to remove TSE infectivity from blood.
TUR-004 is intended for use as an adjunctive therapy for refractory generalized seizures in patients with epileptic encephalopathies.
Transmissible spongiform encephalopathies have perhaps the most unconventional natural history of any infectious agent.
The labeling states that the manufacture of Gamunex(R), which incorporates the innovative Caprylate/Chromatography process for improved product purity and prolonged biological activity, provides reasonable assurance that potential infection risk is significantly reduced from pathogenic prions associated with Transmissible Spongiform Encephalopathies (TSEs), such as vCJD, in the unlikely event they are present in donated plasma.
Prion diseases, also known as transmissible spongiform encephalopathies, are rapidly progressive, uniformly fatal brain diseases that can infect humans and animals, including cattle, sheep, goats, mink, deer, elk, cats, and zoo ungulates.
The Company will be funding a research study to clean the meat and plasma (blood) supply of scrapie infectivity, the agent believed to cause Transmissible Spongiform Encephalopathies (TSE's).
An update on Transmissible Spongiform Encephalopathies (TSEs), including variant Creutzfeldt-Jakob Disease (vCJD), the human form of "mad cow" disease, was a key topic at the Food & Drug Administration's Blood Products Advisory Committee meeting in Gaithersburg, Maryland today.
We present the results of mouse bioassay studies to show that, contrary to findings in cattle with BSE in which the tissue distribution of infectivity is the most limited recorded for any of the transmissible spongiform encephalopathies (TSE), infectivity in greater kudu with BSE is distributed in as wide a range of tissues as occurs in any TSE.
Brown, a senior research scientist at the National Institute of Neurological Disorders and Stroke, has done extensive research on virtually all aspects of the Transmissible Spongiform Encephalopathies (TSE's), including bovine spongiform encephalopathy (or mad cow disease) and the human form of the disease -- Creutzfeldt-Jakob disease -- during his long, distinguished career.