Few patients had extrapyramidal and/or pyramidal sequelae due to the progression to encephalitis lethargica
(8), (14) (8%) and acute necrotizing encephalopathy (8%), (16), (21) or following severe encephalopathy (4%).
Having suffered nervous breakdowns, Peake began to display the symptoms of Parkinson's disease and a rare condition known as encephalitis lethargica
which impaired his ability to draw.
Crosby, an author and writer whose grandmother was killed by encephalitis lethargica
, or "sleeping sickness," examines the mysterious epidemic which killed about one million people around the world in the 1920s, mostly in New York City.
The neuroleptic drugs "induce a brain pathology, similar in kind to encephalitis lethargica
and Parkinson's disease.
After the encephalitis lethargica
pandemic from 1917 to 1926, depression, mania, and obsessive-compulsive disorder were observed in postencephalitis patients (11).
The doctors had diagnosed encephalitis lethargica
, popularly but inaccurately called ``sleeping illness'', the terrible condition which spread through North America and Europe with the Spanish influenza pandemic which killed 50 million people after World War One .